… The aim of this study was to determine the impact of ABCB1 (MDR1… we can infer that
amlodipine pharmacokinetics is affected by … Kim et al suggested that haplotype analysis rather …

… to ABCB1, CYP3A5. Materials and methods. Antihypertensive efficacy and tolerability of
amlodipine was evaluated in 100 patients … on the genotypes of the ABCB1 and CYP3A5 genes. …

… effect of CYP3A4*1G, CYP3A5*3, and MDR1 C3435T gene polymorphisms on the
pharmacokinetics of amlodipine in hypertensive patients … effect of different genotype and …

… CYP3A5 does not affect the pharmacokinetic variability of amlodipine [22… ABCB1 gene (also
known as multi drug resistance 1; MDR1) … The haplotype analysis data suggested that SNPs …

… of this protein determines the pharmacokinetics of drugs and, … of polymorphisms C3435T,
G2677T, C1236T of the MDR1 gene … Patients with genotypic affiliation with / T made up a huge …

… essential for comprehending drug pharmacokinetics and optimizing … of polymorphisms
C3435T, G2677T, C1236T of the MDR1 … Patients with genotypic affiliation with / T made up a huge …

… membrane of the hepatocyte, the ABCB1 (MDR1/Pgp) ATP-binding … hypothesized that small
pharmacokinetic differences might … and a capillary blood sample obtained for PCR analysis. …

… The transporter involved in the efflux of amlodipine is multidrug resistance 1 (MDR1) and …
24 h after dosing, and additional 48- and 72-h visits were made for pharmacokinetic sampling. …

… patients to improve pharmacotherapy with chronic gastritis by the MDR1 gene, which provides
the pharmacokinetics … our results and the data obtained by the standardized test system of …

… Drug-free K 3 EDTA human plasma samples were harvested on-site from healthy volunteers…
Similarly the deduced pharmacokinetic parameters of HCT came in close agreement with …